Publications | Abrol Lab

2025

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release

Tawfeeq C, Hilibrand AS, Smith JS, Portillo J, Kruse AC, Abrol R*

Biochemistry, 64(11):2439–2454 (2025)

PMID: 40358213

G Protein Selectivity in Dopamine Receptors

Journal Article

IgStrand: A universal residue numbering scheme for the immunoglobulin-fold (Ig-fold) to study Ig-proteomes and Ig-interactomes

Tawfeeq C, Wang J, Khaniya U, Madej T, Song J, Abrol R*, Youkharibache P

PLoS Comput Biol, 21(4):e1012813 (2025)

PMID: 40228037

Journal Article

Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth

Alonso-Valenteen F, Mikhael S, Wang H, Sims J, Taguiam M, Teh J, Sances S, Wong M, Miao T, Srinivas D, Gonzalez-Almeyda N, Cho RH, Sanchez R, Nguyenle K, Serrano E, Ondatje B, Benhaghnazar RL, Gray HB, Gross Z, Yu J, Svendsen CN, Abrol R, Medina-Kauwe LK

Nature Nanotechnol, 20(5):683–696 (2025)

PMID: 39984637

Systemic HER3 ligand-mimicking nanobioparticles

Journal Article

Thermodynamic role of receptor phosphorylation barcode in cannabinoid receptor desensitization

Heo EH, Abrol R

Biochem Biophys Res Commun, 743:151100 (2025)

PMID: 39693934

Thermodynamic role of receptor phosphorylation barcode

Journal Article

The Complementary Roles of CXCR4 and CXCR7 in Melanoma Migration

Lacap R, Yousefi N, Hain S, Dahan N, Tran T, Gorgy J, Caguioa R, Malone CS, Abrol R, de Bellard ME

OALib Journal (2025)

PMID: N/A

The Complementary Roles of CXCR4 and CXCR7 in Melanoma Migration

Journal Article

2024

Ig or Not Ig? That Is the Question: The Nucleating Supersecondary Structure of the Ig-Fold and the Extended Ig Universe

Wang J, Abrol R, Youkharibache P

Methods Mol Biol, 2870:371–396 (2024)

PMID: 39543045

Journal Article

Identification of Gα12- vs- Gα13-coupling determinants and development of a Gα12/13-coupled designer GPCR

Tatsumi M, Cruz C, Kamakura N, Kuwabara R, Nakamura G, Ikuta T, Abrol R, Inoue A

Scientific Reports, 14(1):11119 (2024)

PMID: 38750247

Identification of Gα12-vs-Gα13-coupling determinants

Journal Article

Towards a structural and functional analysis of the immunoglobulin-fold proteome

Tawfeeq C, Song J, Khaniya U, Madej T, Wang J, Youkharibache P, Abrol R*

Adv Protein Chem Struct Biol, 138:135–178 (2024)

PMID: 38220423

Towards a structural and functional analysis of the immunoglobulin-fold proteome

Review Article

2022

Three-stage model of helical membrane protein folding: Role of membrane–water interface as the intermediate vestibule for TM helices during their in membrano assembly

Kawamala B-K, Abrol R*

Biochem Biophys Res Commun, 624:1–7 (2022)

PMID: 35926384

Journal Article

2021

Development of Enhanced Conformational Sampling Methods to Probe the Activation Landscape of GPCRs

Abrol R*, Serrano E, Santiago LJ

Membrane Proteins (Adv Protein Chem Struct Biol), Ed. Rossen Donev, 128:325–359 (2021)

PMID: 35034722

Review Article

2020

The complex role of the N-terminus and acidic residues of HdeA as pH-dependent switches in its chaperone function

Pacheco S, Widjaja MA, Gomez JS, Crowhurst KA, Abrol R*

Biophysical Chemistry, 264:106406 (2020)

PMID: 32593908

Journal Article

Pseudo-Symmetric Assembly of Protodomains as a Common Denominator in the Evolution of Polytopic Helical Membrane Proteins

Youkharibache P, Tran A, Abrol R*

Journal of Molecular Evolution, 88(4):319–344 (2020)

PMID: 32189026

Journal Article

2019

Understanding G protein selectivity of muscarinic acetylcholine receptors using computational methods

Santiago LJ, Abrol R*

Int J Mol Sci, 20(21):E5290 (2019)

PMID: 31653051

Journal Article

HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo

Alonso-Valenteen F, Pacheco S, Srinivas D, Rentsendorj A, Chu D, Lubow J, Sims J, Miao T, Mikhael S, Hwang JY, Abrol R*, Medina-Kauwe L

Nucleic Acids Research, 47(21):11020–11043 (2019)

PMID: 31617560

Journal Article

A beetle antifreeze protein protects lactate dehydrogenase under freeze-thawing

Rodriguez C, Sajjadi S, Abrol R*, Wen X

Int J Biol Macromolecules, 136:1153–1160 (2019)

PMID: 31226372

Journal Article

Chiral Graphs: Reduced Representations of Ligand Scaffolds for Stereoselective Biomolecular Recognition, Drug Design, and Enhanced Exploration of Chemical Structure Space

Mikhael S, Abrol R*

ChemMedChem, 14(8):798–809 (2019)

PMID: 30821046 Invited Communication

Journal Article