We do precise guesswork!

Welcome to the Abrol Lab! We are a computational biophysical chemistry group at California State University, Northridge, dedicated to understanding the molecular mechanisms of G protein–coupled receptors (GPCRs). Our research focuses on using and developing computational methods to study protein structure, dynamics, and function at the atomistic level. By combining molecular modeling, molecular dynamics simulations, and data-driven analyses, we aim to uncover how GPCR conformational changes influence drug binding and signal transduction. Our work contributes to the broader goal of advancing rational drug design and deepening our understanding of fundamental biochemical processes.